Rury R Holman Selected Research

Exenatide (Byetta)

1/2022	A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk.
1/2022	Lifetime cost-effectiveness simulation of once-weekly exenatide in type 2 diabetes: A cost-utility analysis based on the EXSCEL trial.
1/2021	Effect of once-weekly exenatide on hospitalization for acute coronary syndrome or coronary revascularization in patients with type 2 diabetes mellitus.
1/2021	Cardiovascular and renal safety of metformin in patients with diabetes and moderate or severe chronic kidney disease: Observations from the EXSCEL and SAVOR-TIMI 53 cardiovascular outcomes trials.
1/2020	Exploring the Possible Impact of Unbalanced Open-Label Drop-In of Glucose-Lowering Medications on EXSCEL Outcomes.
1/2020	Prediction and validation of exenatide risk marker effects on progression of renal disease: Insights from EXSCEL.
1/2020	Confirming the Bidirectional Nature of the Association Between Severe Hypoglycemic and Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL.
1/2020	Within-Trial Evaluation of Medical Resources, Costs, and Quality of Life Among Patients With Type 2 Diabetes Participating in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).
12/2019	Clinical Outcomes in Patients With Type 2 Diabetes Mellitus and Peripheral Artery Disease: Results From the EXSCEL Trial.
11/2019	Effect of Once-Weekly Exenatide in Patients With Type 2 Diabetes Mellitus With and Without Heart Failure and Heart Failure-Related Outcomes: Insights From the EXSCEL Trial.

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Rury R Holman Research Topics

Disease

96	Type 2 Diabetes Mellitus (MODY) 01/2022 - 02/2002
40	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 05/2002
23	Myocardial Infarction 01/2022 - 10/2008
21	Stroke (Strokes) 12/2020 - 04/2010
20	Heart Failure 01/2022 - 12/2006
20	Glucose Intolerance 12/2020 - 10/2006
11	Insulin Resistance 01/2021 - 10/2002
9	Hypoglycemia (Reactive Hypoglycemia) 12/2019 - 02/2002
8	Atrial Fibrillation 10/2021 - 01/2012
7	Hypertension (High Blood Pressure) 01/2022 - 11/2004
7	Unstable Angina 12/2019 - 04/2010
7	Diabetes Mellitus 12/2019 - 07/2006
7	Weight Gain 01/2018 - 02/2002
6	Hyperglycemia 05/2012 - 05/2002
5	Body Weight (Weight, Body) 01/2022 - 02/2002
5	Coronary Disease (Coronary Heart Disease) 12/2020 - 09/2013
5	Renal Insufficiency (Renal Failure) 01/2020 - 06/2013
4	Neoplasms (Cancer) 01/2022 - 11/2017
4	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022 - 11/2004
4	Vascular Diseases (Vascular Disease) 12/2021 - 01/2016
4	Obesity 01/2020 - 08/2006
4	Blindness (Hysterical Blindness) 01/2020 - 06/2013
4	Pancreatitis 01/2018 - 02/2017
3	Albuminuria 10/2021 - 06/2006
3	Peripheral Arterial Disease 10/2021 - 03/2009
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 07/2020 - 06/2006
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018 - 02/2017
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017 - 08/2006
3	Overweight 04/2015 - 11/2006
2	Weight Loss (Weight Reduction) 01/2022 - 04/2015
2	Infections 10/2021 - 01/2020
2	Chronic Renal Insufficiency 01/2021 - 11/2017
2	Acute Coronary Syndrome 01/2021 - 01/2020
2	Inflammation (Inflammations) 01/2020 - 08/2006
2	Edema (Dropsy) 01/2018 - 12/2006
2	Eye Diseases (Eye Disease) 11/2017 - 07/2006
2	Bone Fractures (Bone Fracture) 11/2017 - 01/2010
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2017 - 01/2017
2	Diabetes Complications 06/2013 - 11/2006
1	Rheumatoid Arthritis 01/2022
1	Gangrene 10/2021
1	Peripheral Vascular Diseases (Peripheral Vascular Disease) 10/2021
1	Foot Ulcer 10/2021
1	Coronary Artery Disease (Coronary Atherosclerosis) 10/2021
1	Orthostatic Hypotension (Postural Hypotension) 01/2021
1	Lactic Acidosis 01/2021

Drug/Important Bio-Agent (IBA)

30	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 08/2002
24	Sitagliptin Phosphate (Januvia)FDA Link 01/2022 - 12/2013
18	Exenatide (Byetta)FDA Link 01/2022 - 04/2016
18	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 10/2002
15	Valsartan (Vals)FDA Link 10/2020 - 10/2008
14	Nateglinide (Starlix)FDA LinkGeneric 10/2020 - 10/2008
12	Insulin (Novolin)FDA Link 10/2021 - 02/2002
9	LipidsIBA 01/2022 - 07/2006
9	LDL CholesterolIBA 10/2021 - 06/2006
9	Pharmaceutical PreparationsIBA 12/2020 - 10/2002
8	HDL CholesterolIBA 01/2022 - 05/2002
8	Rosiglitazone (Avandia)FDA Link 05/2011 - 10/2002
7	CreatinineIBA 01/2022 - 06/2006
7	Hypoglycemic Agents (Hypoglycemics)IBA 01/2020 - 10/2007
6	omega-Chloroacetophenone (Mace)IBA 12/2021 - 01/2019
6	Dipeptidyl-Peptidase IV InhibitorsIBA 12/2020 - 07/2015
6	Glyburide (Glibenclamide)FDA LinkGeneric 05/2011 - 10/2002
5	Hemoglobins (Hemoglobin)IBA 01/2022 - 12/2013
5	Acarbose FDA LinkGeneric 10/2021 - 07/2014
5	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2021 - 01/2018
5	ThiazolidinedionesIBA 10/2020 - 12/2006
4	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2010
4	Glucagon-Like Peptide-1 ReceptorIBA 12/2019 - 04/2016
4	Triglycerides (Triacylglycerol)IBA 01/2018 - 01/2004
4	C-Reactive ProteinIBA 02/2014 - 10/2002
4	AlbuminsIBA 01/2012 - 10/2002
3	SodiumIBA 01/2021 - 10/2019
3	Sodium-Glucose Transporter 2 InhibitorsIBA 12/2020 - 10/2019
3	Blood Glucose (Blood Sugar)IBA 07/2020 - 02/2014
3	Retinaldehyde (Retinal)IBA 01/2020 - 11/2002
3	GlucosidasesIBA 01/2020 - 07/2014
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2019 - 03/2009
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 09/2017 - 02/2014
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 09/2017 - 11/2004
3	CholesterolIBA 01/2012 - 08/2006
3	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 10/2009 - 12/2006
2	empagliflozinIBA 01/2021 - 01/2020
2	AutoantibodiesIBA 01/2020 - 11/2006
2	Glucagon-Like Peptide 1 (GLP 1)IBA 12/2019 - 01/2017
2	Glycoside Hydrolase InhibitorsIBA 10/2019 - 01/2018
2	Angiotensin Receptor AntagonistsIBA 09/2017 - 10/2012
2	AntigensIBA 08/2006 - 10/2002
2	Fibrinogen (Factor I)FDA Link 08/2006 - 10/2002
1	AnthracyclinesIBA 01/2022
1	Fenofibrate (CiL)FDA LinkGeneric 01/2022

Therapy/Procedure

34	Therapeutics 01/2022 - 02/2002
11	Glycemic Control 01/2020 - 02/2002
5	Surgical Amputation (Amputations) 10/2021 - 06/2013
4	Light Coagulation 01/2020 - 11/2002
3	Precision Medicine 01/2022 - 01/2018
2	Drug Therapy (Chemotherapy) 01/2022 - 12/2006
2	Secondary Prevention 11/2017 - 09/2017
1	Lasers (Laser) 01/2022
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2022